A woman has died following a single-vehicle crash in Yuroke this morning.

A vehicle was travelling along Mickleham Road when it left the road and struck a tree then rolled around 1.30am.

Despite the best efforts of emergency services, the sole occupant who is yet to be formally identified, died at the scene.

Police will prepare a report for the coroner.

In only the first 12 days of 2022, 10 lives have been lost on Victorian roads, up from four at the same time last year.