Police are investigating a fatal crash on the Northern Highway at Moranding this afternoon.
It is understood a car and a truck collided on the highway at about 4.15pm.
The driver and sole occupant of the car died at the scene.
They are yet to be formally identified.
The truck driver sustained minor injuries and has been taken to hospital for treatment.
Police are yet to determine the exact cause of the collision and investigations remain ongoing.
The Northern Highway is closed in both directions between the Broadford-Kilmore Road roundabout and Whitegate Road, High Camp, due to the crash.
Motorists travelling between Kilmore and Tooborac should divert using Broadford-Kilmore Road, Hume Freeway and Seymour-Tooborac Road. Lancefield-Kilmore Road and Lancefield-Tooborac Road provides another alternative.
The road will re-open when investigations are complete and it is safe to do so.
Anyone who witnessed the incident or has information is urged to contact Crime Stoppers on 1800 333 000 or submit a confidential report online at www.crimestoppersvic.com.au.
Real-time traffic conditions are available at traffic.vicroads.vic.gov.au.
